## Background: Informed consent is critical to the ethical conduct of pediatric cancer clinical research. research regarding such consent has been limited. ## Methods: After conducting a background survey of institutional practice from principal investigators (pis) at 113 childrens cancer group (
Informed consent in advanced laryngeal cancer
โ Scribed by Robert L. Foote; Paul D. Brown; Yolanda I. Garces; Scott H. Okuno; Robert C. Miller; Scott E. Strome
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 189 KB
- Volume
- 29
- Category
- Article
- ISSN
- 1043-3074
No coin nor oath required. For personal study only.
โฆ Synopsis
Abstract
Purpose.
This study was designed to evaluate the relationship between the informed consent process and the treatment received by patients with advanced laryngeal cancer.
Methods.
The study group was composed of 101 consecutive patients who were eligible for the Department of Veterans Affairs Laryngeal Cancer Study Group and Radiation Therapy Oncology Group/Head and Neck Intergroup (RTOG 91โ11) larynx preservation clinical trials and who underwent treatment at the Mayo Clinic during the years 1985 to 2000. Records were reviewed to evaluate the effect that referral to an oncologist, discussion and documentation of treatment alternatives by the surgeon, offering a chance at a larynx conservation surgical procedure, and treatment recommendation made by the surgeon have on the treatment chosen and received by the patient.
Results.
Discussion of treatment alternatives by the surgeon (p = .0054), referral to an oncologist (p < .0001), offering a chance for a larynx conservation surgical procedure (p = .047), and treatment recommended by the surgeon (p < .0001) were significantly related to the treatment received by the patient.
Conclusion.
The treatment received by a patient with advanced laryngeal cancer is determined by the treatment recommended by the surgeon, referral to an oncologist, discussion of treatment alternatives by the surgeon, and offering a chance for a larynx conservation surgical procedure. ยฉ 2007 Wiley Periodicals, Inc. Head Neck 29:, 2007.
๐ SIMILAR VOLUMES
## Abstract ## Introduction Cancer patients often have concurrent diseases and conditions known as comorbidities. The aim of this project is to demonstrate the significance of comorbidity in the treatment and outcomes of advanced laryngeal carcinoma. ## Methods A retrospective medical record rev