Information theory of chromatography and titration

✍ Scribed by Yuzuru Hayashi; Rieko Matsuda

• Publisher: Elsevier Science
• Year: 1993
• Tongue: English
• Weight: 616 KB
• Volume: 277
• Category: Article
• ISSN: 0003-2670
• DOI: 10.1016/0003-2670(93)80445-q

✦ Synopsis

The function of mutual information, abbreviated as FUMI, is a function of peak parameters (width, area and position, if the peak is Gaussian), separation (resolution RF) and noise variance of an output of an analytical system (e.g. chromatogram). For quantitative analysis, FUMI describes the precision (or relative standard deviation) of measurements as the Shannon mutual information. FUMI theoretically confirms that a high, sharp, well-separated peak gives a reliable measurement (e.g. concentration). The higher the FUMI for a peak, the more precise is the measurement obtained from the peak. This paper demonstrates that chemically different analytical methods intended for quantification, LC and titration, can be evaluated in a general way with FUMI as a criterion.