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Influenza virus-specific human cytotoxic T cell clones: Heterogeneity in antigenic specificity and restriction by class II MHC products

✍ Scribed by David R. Kaplan; Rogers Griffith; Vivian L. Braciale; Thomas J. Braciale

Book ID
113132841
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
1024 KB
Volume
88
Category
Article
ISSN
0008-8749

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Human T lymphocyte clones (TLC) specific for diphtheria toxoid (DT) were isolated from a DR6/7 individual by cloning in soft agar in vivo sensitized T lymphocytes. We report here the isolation and characterization of 3 of these clones by studying: (a) the kinetic of activation, (b) the surface pheno