Computational studies of H5N1 influenza
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Nick X. Wang; Jie J. Zheng
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Article
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2009
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Cold Spring Harbor Laboratory Press
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English
β 433 KB
## Abstract Influenza A (H5N1) virus is one of the world's greatest pandemic threats. Neuraminidase (NA) inhibitors, oseltamivir and zanamivir, prevent the spread of influenza, but drugβresistant viruses have reduced their effectiveness. Resistance depends on the binding properties of NAβdrug compl