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Influences of pH operation conditions on human growth hormone production by recombinant Bacillus subtilis

✍ Scribed by Yılmaz, Özge Deniz; Çalık, Güzide; Özdamar, Tunçer H.


Book ID
123000391
Publisher
Elsevier
Year
2012
Tongue
English
Weight
70 KB
Volume
29
Category
Article
ISSN
1871-6784

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We demonstrate for the first time, an expression system mimicking serine alkaline protease synthesis and secretion, producing native form of human growth hormone (hGH) from Bacillus subtilis. A hybrid-gene of two DNA fragments, i.e., signal (pre-) DNA sequence of B. licheniformis serine alkaline pro