𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Influence of pH on recombinant human growth hormone production by Pichia pastoris

✍ Scribed by Pınar Çalık; Eda Bayraktar; Bahar İnankur; Elif Ş. Soyaslan; Merve Şahin; Hatice Taşpınar; Eda Açık; Remziye Yılmaz; Tunçer H. Özdamar


Publisher
Wiley (John Wiley & Sons)
Year
2010
Tongue
English
Weight
267 KB
Volume
85
Category
Article
ISSN
0268-2575

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Fermentation and oxygen transfer charact
✍ Pınar Çalık; Bahar İnankur; Elif Ş. Soyaslan; Merve Şahin; Hatice Taşpınar; Eda 📂 Article 📅 2009 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 194 KB

## Abstract **BACKGROUND:** The influence of methanol feed rate on recombinant human growth hormone (rhGH) production by __Pichia pastoris__ hGH‐Mut^+^ in medium containing sorbitol was investigated at three different specific growth rates (µ), namely, 0.02 (MS‐0.02), 0.03 (MS‐0.03), and 0.04 (MS‐0

Influence of specific growth rate on spe
✍ Jonas Schenk; Krisztina Balazs; Carmen Jungo; Julien Urfer; Carole Wegmann; Andr 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 195 KB 👁 2 views

## Abstract A recombinant avidin‐producing Mut^+^ __Pichia pastoris__ strain was used as a model organism to study the influence of the methanol feeding strategy on the specific product productivity (q~p~) and protein glycosylation. Fed‐batch cultivations performed at various specific growth rates

Influence of scale-up on the quality of
✍ F. Bylund; A. Castan; R. Mikkola; A. Veide; G. Larsson 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 232 KB 👁 2 views

The aerobic fed-batch production of recombinant human growth hormone (rhGH) by Escherichia coli was studied. The goal was to determine the production and protein degradation pattern of this product during fed-batch cultivation and to what extent scale differences depend on the presence of a fed-batc

Modeling Pichia pastoris growth on metha
✍ Wenhui Zhang; Mark A. Bevins; Bradley A. Plantz; Leonard A. Smith; Michael M. Me 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 156 KB 👁 2 views

An unstructured growth model for the recombinant methylotrophic yeast P. pastoris Mut + expressing the heavy-chain fragment C of botulinum neurotoxin serotype A [BoNT/A(H c )], was successfully established in quasi-steady state fed-batch fermentations with varying cell densities. The model describes

INTERLEUKIN-6-INDUCED PRODUCTION OF TYPE
✍ Beata Derfalvi; Peter Igaz; Kristof A Fulop; Csaba Szalai; Andras Falus 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 222 KB

## Abstract Growth hormone (GH), given therapeutically in many human diseases, is able to modulate the maturation and function of many cells of immune system. The present study demonstrates the effect of human recombinant GH on the production of acute phase proteins (APP) as well as on the gene exp