Influence ofβ-endorphin on preimplantation development of mouse embryos in vitro
✍ Scribed by A. S. Chernov; Yu. A. Kovalitskaya; N. Yu. Sakharova; L. M. Chailakhyan
- Book ID
- 110159652
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 183 KB
- Volume
- 428
- Category
- Article
- ISSN
- 0012-4966
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## Abstract The optimal oxygen tension for development of preimplantation mouse embryos to the blastocyst stage in vitro was found to be between 2.5% and 5%. One‐ and two‐cell embryos had a more sharply defined range of oxygen tension capable of supporting development than 8‐cell and morula stages.
Mouse preimplantation embryos consume pyruvate preferentially during the early developmental stages, before glucose becomes the predominant energy substrate in the blastocyst. To investigate the importance of the switch to glucose utilization at the later developmental stages, mouse embryos from F1