✦ LIBER ✦

Influence ofGSTM1genotypes onanti-BPDE–DNA adduct levels in mononuclear white blood cells of humans exposed to PAH

✍ Scribed by S. Pavanello; G. Gabbani; G. Mastrangelo; F. Brugnone; G. Maccacaro; E. Clonfero

Book ID: 106103041
Publisher: Springer-Verlag
Year: 1999
Tongue: English
Weight: 130 KB
Volume: 72
Category: Article
ISSN: 0340-0131
DOI: 10.1007/s004200050367

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Polymorphisms of the GSTP1 and GSTM1 gen

Polymorphisms of the GSTP1 and GSTM1 genes and PAH-DNA adducts in human mononuclear white blood cells

✍ Dorota Butkiewicz; Ewa Grzybowska; David H. Phillips; Kari Hemminki; Mieczysław 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 77 KB 👁 2 views

Glutathione S-transferases (GSTs) are an important part of the protection system against a wide range of potentially harmful chemical compounds. GSTP1 and GSTM1 are mainly involved in detoxification reactions of PAH carcinogenic intermediates produced by cytochrome P450 (CYP). Polymorphism of the GS

GSTM1 null genotype as a risk factor for

GSTM1 null genotype as a risk factor for anti-BPDE-DNA adduct formation in mononuclear white blood cells of coke-oven workers

✍ Sofia Pavanello; Ewa Siwinska; Danuta Mielzynska; Erminio Clonfero 📂 Article 📅 2004 🏛 Elsevier Science 🌐 English ⚖ 115 KB

Influence of GSTM1 null and low repair X

Influence of GSTM1 null and low repair XPC PAT+ on anti-B[a]PDE-DNA adduct in mononuclear white blood cells of subjects low exposed to PAHs through smoking and diet

✍ Sofia Pavanello; Alessandra Pulliero; Erminio Clonfero 📂 Article 📅 2008 🏛 Elsevier Science 🌐 English ⚖ 154 KB

Modulation of DNA adduct levels in human

Modulation of DNA adduct levels in human mononuclear white blood cells and granulocytes by CYP1A1, CYP2D6 and GSTM1 genetic polymorphisms

✍ Dorota Butkiewicz; Ewa Grzybowska; Kari Hemminki; Steinar Øvrebø; Aage Haugen; G 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 205 KB

The impact of glutathione s-transferase

The impact of glutathione s-transferase M1 and cytochrome P450 1A1 genotypes on white-blood-cell polycyclic aromatic hydrocarbon-dna adduct levels in humans

✍ Nathaniel Rothman; Peter G. Shields; Miriam C. Poirier; Anita M. Harrington; D. 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 616 KB

## Abstract Carcinogenic polycyclic aromatic hydrocarbons(a) form DNA adducts via a complex metabolic activation pathway that includes cytochrome P450(a) 1A1, whereas intermediate metabolites can be detoxified by conjugation through pathways including glutathione s‐transferase M1 (GSTM1). PAH‐DNA a