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Influence of zeaxanthin and echinenone binding on the activity of the Orange Carotenoid Protein

✍ Scribed by Claire Punginelli; Adjélé Wilson; Jean-Marc Routaboul; Diana Kirilovsky

Book ID
113484369
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
1023 KB
Volume
1787
Category
Article
ISSN
0005-2728

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The effect of variable protein binding (taken as independent parameter) on pharmacological activity of drugs is considered in terms of the exposure or the steady state concentration of unbound drug at targeted tissue. Based on the application of the parallel tube or dispersion models it is shown tha