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Influence of TP53 gene status on treatment response in breast cancer cells

✍ Scribed by L. Fernández; S. Ghayad; P. Cohen; P. Hainaut; M. Olivier

Book ID
119598801
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
85 KB
Volume
6
Category
Article
ISSN
1359-6349

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## Abstract Mutations in the tumor suppressor gene __TP53__ are associated with poor prognosis in breast cancer. This prognostic value may rely in part on the fact that p53 plays a role in the antiproliferative and apoptotic activities of chemotherapy regimens used to treat breast tumors. However,