Influence of thrombin-activatable fibrinolysis inhibitor and plasminogen activator inhibitor-1 gene polymorphisms on tissue-type plasminogen activator-induced recanalization in ischemic stroke patients
β Scribed by I. FERNANDEZ-CADENAS; J. ALVAREZ-SABIN; M. RIBO; M. RUBIERA; M. MENDIOROZ; C. A. MOLINA; A. ROSELL; J. MONTANER
- Book ID
- 109152232
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 585 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1538-7933
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The effects were examined of baicalein on tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor-1 (PAI-1) production stimulated by interleukin-1β£ (IL-1β€) and tumour necrosis factor-β£ (TNF-β£) in cultured human vein umbilical endothelial cells (HUVECs). IL-1β€ and TNF-β£ increased
## Objective: To investigate the relationship between the 4g/5g polymorphism of the type 1 plasminogen activator inhibitor (pai-1) gene and thrombotic manifestations in patients with antiphospholipid syndrome (aps). ## Methods: We studied a total of 247 patients included in the following 4 groups