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Influence of the schedule of exposure on the cytotoxic effect of melphalan on human 8226 and A2780 cells

✍ Scribed by F Pinguet; F Bressolle; S Culine; M Fabbro; C Astre; C Chevillard


Book ID
117666811
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
103 KB
Volume
35
Category
Article
ISSN
0959-8049

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In human tumor cells freshly obtained from patients with breast cancer, ovarian cancer, or adenocarcinoma of unknown etiology and in normal human bone marrow cells, the cell-to-medium ratio (intracellular/extracellular concentration) in vitro of 5.42 microM melphalan rose rapidly to levels of 6-17 a