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Influence of the N3-Protection Group on N1- vs. O2-Alkylation in the Mitsunobu Reaction

โœ Scribed by Olaf R. Ludek; Chris Meier


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
126 KB
Volume
2006
Category
Article
ISSN
1434-193X

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## Abstract The __Mitsunobu__ reaction is an important tool in carbocyclic nucleoside chemistry for the direct coupling of alcohols with heterocyclic bases under mild conditions. Chemical evidences for an unusual competitive __O__^2^โ€ __vs. N__^1^โ€alkylation of 3โ€substituted pyrimidines is presente