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Influence of the culture conditions of brucella abortus on its antitumor properties

✍ Scribed by B. Collet; L. Dazord; J. Portoukalian; F. Sauvager; A. Ruffault; C. David

Publisher
Springer-Verlag
Year
1983
Tongue
English
Weight
355 KB
Volume
14
Category
Article
ISSN
0340-7004

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✦ Synopsis

A heat-inactivated rough mutant of B. abortus increased resistance to a transplantable lymphoma when cultured on solid agar (ag) but not when cultured on a fluid medium (fl). The ag organisms were smaller, more toxic and induced more interferon 2 h after injection than fl. They also contained a phospholipid (cardiolipin) absent from fl preparations.

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