𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Influence of Substrate Binding on the Mechanical Stability of Mouse Dihydrofolate Reductase

✍ Scribed by Junker, J.P.; Hell, K.; Schlierf, M.; Neupert, W.; Rief, M.

Book ID
119919876
Publisher
Biophysical Society
Year
2005
Tongue
English
Weight
208 KB
Volume
89
Category
Article
ISSN
0006-3495

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Electron redistribution on binding of a
Electron redistribution on binding of a substrate to an enzyme: Folate and dihydrofolate reductase
✍ JΓΌrgen Bajorath; David H. Kitson; George Fitzgerald; Jan Andzelm; Joseph Kraut; πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 893 KB

## Abstract The migration of electron density of a substrate (folate) on binding to an enzyme (dihydrofolate reductase) is studied by a quantum‐mechanical method originally developed in solid state physics. A significant polarization of the substrate is induced by the enzyme, toward the transition