𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Influence of rat strain on P-glycoprotein expression in cultured hepatocytes

✍ Scribed by E. Chieli; N. Romiti; F. Cervelli; A. Paolicchi; R. Tongiani


Publisher
Springer
Year
1994
Tongue
English
Weight
328 KB
Volume
10
Category
Article
ISSN
0742-2091

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Effect of interferons on P-glycoprotein-
✍ Yukiko Akazawa; Hiroko Kawaguchi; Maki Funahashi; Yoshihiko Watanabe; Kiyoshi Ya πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 139 KB

The effect of interferon (IFN)-beta and IFN-gamma on P-glycoprotein (P-gp)-mediated efflux of rhodamin-123(Rho-123), a typical substrate of P-gp, was studied in rat hepatocytes in primary culture. After treatment with IFN-beta, IFN-gamma, or both for 3 days, steady-state levels of Rho-123, incorpora

Induction of mdr1b mRNA and P-glycoprote
✍ Karen I. Hirsch-Ernst; Christina Ziemann; Heidi Foth; Detlef Kozian; Christoph S πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 248 KB πŸ‘ 2 views

Mammalian liver exhibits expression of members of the family of multidrug resistance (mdr) transporters (P-glycoproteins). P-glycoprotein isoforms encoded by mdr1 genes participate in extrusion of an array of xenobiotics into the bile. Induction of mdr1b mRNA expression has been shown to occur in ra

Phenobarbital induction of Ξ±1-acid glyco
✍ Thierry Fournier; Najet Mejdoubi; Dagui Monnet; GeneviΓ¨ve Durand; Dominique Porq πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 582 KB

The serum level of rat a,-acid glycoprotein is significantly increased by treatment with phenobarbital, and in uiuo studies have shown that phenobarbital seems to act mainly at the transcriptional level. To show the direct mediating effect of phenobarbital on a,-acid glycoprotein gene expression, we