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Influence of Phenytoin and phenobarbital on the disposition of a single oral dose of clonazepam

✍ Scribed by Khoo, Ko-Chin; Mendels, Joseph; Rothbart, Myer; Garland, William A; Colburn, Wayne A; Min, Bo H; Lucek, Rudolph; Carbone, John J; Boxenbaum, Harold G; Kaplan, Stanley A

Book ID
109842877
Publisher
Nature Publishing Group
Year
1980
Tongue
English
Weight
511 KB
Volume
28
Category
Article
ISSN
0009-9236

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Effect of smoking on single dose pharmac
Effect of smoking on single dose pharmacokinetics of phenobarbital
✍ A. Mirfazaelian; F. Jahanzad; M. Tabatabaei-far; H. Farsam; M. Mahmoudian πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 70 KB πŸ‘ 2 views

## Abstract In order to determine interaction of smoking with single dose pharmacokinetics of phenobarbital, a 60 mg tablet of the drug was given to 12 healthy male subjects in two groups (6 smokers and 6 non‐smokers) in a double blind study. An HPLC method using UV detection was developed to asses