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Influence of parasite encoded inhibitors of serine peptidases in early infection of macrophages with Leishmania major

✍ Scribed by Sylvain C. P. Eschenlauer; Marilia S. Faria; Lesley S. Morrison; Nicolas Bland; Flavia L. Ribeiro-Gomes; George A. DosReis; Graham H. Coombs; Ana Paula C. A. Lima; Jeremy C. Mottram


Book ID
109041783
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
444 KB
Volume
11
Category
Article
ISSN
1462-5814

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We recently reported that the infection of macrophages with Leishmania major led to the release of type 1 interferons (IFN- Β§ / g ). Moreover, at day 1 of infection of mice with L. major, IFN- Β§ / g was required for the expression of type 2 (inducible) NO synthase (NOS2 or iNOS) which, however, was