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Influence of p53 and p21WAF1 expression on sensitivity of cancer cells to cladribine

✍ Scribed by Carlos Marı́a Galmarini; Nathalie Voorzanger; Nicole Falette; Lars Jordheim; Emeline Cros; Alain Puisieux; Charles Dumontet


Book ID
113993297
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
299 KB
Volume
65
Category
Article
ISSN
0006-2952

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Influence of p53 expression on sensitivi
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## Abstract In this study, we determined whether p53 expression affected the sensitivity of non–small cell lung cancer (NSCLC) and colon cancer cells to bleomycin (BLM). Two human NSCLC cell lines (A549 expressing wild‐type p53 and p53‐null H1299) and two colon cancer cell lines (HCT116 __p53__+/+