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Influence of Minor Groove Substituents on the Structure of DNA Holliday Junctions †

✍ Scribed by Hays, Franklin A.; Jones, Zebulon J. R.; Ho, P. Shing

Book ID
127301437
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
825 KB
Volume
43
Category
Article
ISSN
0006-2960

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Influence of β-Alanine on Hairpin Polyam
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✍ Victor C. Rucker; Christian Melander; Peter B. Dervan 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 German ⚖ 398 KB

## Abstract Antiparallel polyamides containing 1__H__‐pyrrole, 1__H__‐imidazole, and 3‐hydroxy‐1__H__‐pyrrole amino acids display a preference for minor‐groove binding oriented NC with respect to the 5′‐3′ direction of the DNA helix. We find that replacement of a central Py/Py pair with a __β__/__