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Influence of microRNA deregulation on chaperone-mediated autophagy and α-synuclein pathology in Parkinson's disease

✍ Scribed by Alvarez-Erviti, L; Seow, Y; Schapira, A HV; Rodriguez-Oroz, M C; Obeso, J A; Cooper, J M


Book ID
121509107
Publisher
Nature Publishing Group
Year
2013
Tongue
English
Weight
665 KB
Volume
4
Category
Article
ISSN
2041-4889

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## Abstract The α‐synuclein Rep1 polymorphism was studied in patients and controls in an ethnic Greek population. There was an association of allele 2 with risk of Parkinson's disease (PD; adjusted odd ratio = 3.25; 95% CI = 1.80–5.87). Survival analyses (Cox proportional hazards models) were emplo