In this study the pharmacokinetics and pharmacodynamics of morphine-3-glucuronide (M3G) were investigated in rats after i.v. administration as a bolus dose (86.7 pmol kg-I) and as a constant rate infusion (2.9 pmol h-') over 5 days. After the bolus dose, the clearance (Cl) was 12.1 ~0.6mlmin-\*\*kg,
β¦ LIBER β¦
Influence of hydrochlorothiazide on the pain threshold and on the antinociceptive activity of morphine, in rats
β Scribed by R. Poggioli; A. V. Vergoni; A. Bertolini
- Publisher
- Springer
- Year
- 1985
- Tongue
- English
- Weight
- 225 KB
- Volume
- 41
- Category
- Article
- ISSN
- 1420-682X
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