The effect of second antibody clearance
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R. Barbara Pedley; Roger Dale; Joan A. Boden; Richard H. J. Begent; Pat A. Keep;
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Article
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1989
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John Wiley and Sons
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French
โ 651 KB
Radioimmunotherapy in humans is limited by toxicity to normal tissues, caused by circulating radio-antibody. Second antibody directed against the first (anti-tumor) antibody accelerates clearance of first antibody from normal tissues, and may thus improve the therapeutic ratio. The effect of second