The mechanisms behind tumour regression during ischaemic therapy of liver malignancy are not thoroughly elucidated. Ischaemia-reperfusion injury and release of free radicals is one mechanism suggested. The aim of the present study was to explore whether inhibition of hydroxyl radicals, by complex bi
Influence of hepatic artery ligation on liver tumor growth in rats
✍ Scribed by Goran Carlsson; Larsolof Hafström
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 391 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0022-4790
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Liver tumors, both primary and secondary, receive their main blood supply from the hepatic artery. Hepatic artery ligation (HAL) causes a reduction in tumor growth and tumor necrosis. In this experiment, three different experimental tumors were used to study the effect of hepatic artery ligation at different intervals after the occlusion of the arterial blood supply. Hepatic artery ligation causes a reduction in liver tumor growth for all three tumors but with some variation according to age and type of tumor.
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## Abstract Female rats were divided into six groups: (1) control, (2) one uterine artery (a.) ligated near the utero‐tubal (U‐T) junction, (3) one uterine a. ligated at the level of the cervix, (4) both uterine aa. ligated separately at the U‐T junction, (5) both uterine aa. ligated separately at