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Influence of food and fluid volume on chlorothiazide bioavailability: Comparison of plasma and urinary excretion methods

โœ Scribed by Peter G. Welling; Rashmi H. Barbhaiya

Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
464 KB
Volume
71
Category
Article
ISSN
0022-3549

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๐Ÿ“œ SIMILAR VOLUMES

Pharmacokinetics of hydrochlorothiazide
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โœ Rashmi H. Barbhaiya; William A. Craig; H. Perri Corrick-West; Peter G. Welling ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 474 KB

The bioavailability of hydrochlorothiazide from 50-mg oral tablet doses was examined in healthy male volunteers under fasting and nonfasting conditions. Bioavailability was examined from plasma levels and urinary excretion of unchanged drug. The pharmacokinetics of hydrochlorothiazide in plasma coul

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Comparative bioavailability and pharmacokinetics of hydrochlorothiazide from oral tablet dosage forms, determined by plasma level and urinary excretion methods
โœ R. H. Barbhaiya; R. B. Patel; H. P. Corrick-West; R. S. Joslin; P. G. Welling ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 358 KB ๐Ÿ‘ 2 views

## Abstract The bioavailability and pharmacokinetics of two hydrochlorothiazide products were compared following single 50 mg oral doses to 20 healthy male volunteers. Plasma and urine were assayed for hydrochlorothiazide by a specific and sensitive HPLC method. Plasma profiles of hydrochlorothiazi