Influence of dose on the pharmacokinetics of Cefadroxil
✍ Scribed by E. L. Mariño; A. Dominguez-Gil
- Publisher
- Springer
- Year
- 1980
- Tongue
- English
- Weight
- 362 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0031-6970
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📜 SIMILAR VOLUMES
The pharmacokinetics of cefadroxil and cephalexin were examined following single oral doses of either 250, 500 or 1OOOmg to a total of 36 healthy volunteers. The volunteers were divided into groups of 12 per dose-group and solution doses of cefadroxil or cephalexin were administered after an overnig
The pharmacokinetic behaviour of cefadroxil was dose-dependent in healthy male volunteers following the oral administration of single doses of 5, 15, and 30 mg.kg-1. As the dose of cefadroxil increased from 5 to 15 and 30 mg.kg-1, the peak plasma concentrations, normalized to 5 mg.kg-1, decreased si