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Influence of a circadian-stage-dependent dosing schedule on the pharmacokinetics of isepamicin in humans

✍ Scribed by Yuji Yoshiyama; Teruaki Kobayashi; Shigehiro Ohdo; Nobuya Ogawa; Michel G. Bergeron; Gaston Labrecque; Denis Beauchamp; Shigeyuki Nakano

Publisher
Springer
Year
1996
Tongue
English
Weight
306 KB
Volume
2
Category
Article
ISSN
1341-321X

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✍ P. E. LΓΈnning; P. M. Ueland; S. Kvinnsland πŸ“‚ Article πŸ“… 1986 πŸ› Springer 🌐 English βš– 508 KB

The pharmacokinetics of the optical enantiomers of warfarin (R-warfarin and S-warfarin) were investigated in patients treated for breast cancer with aminoglutethimide (AG). The patients received 125 mg AG b.i.d. (i.e., low-dosage regimen); 250 mg AG q.i.d. together with cortisone acetate (i.e. high-