Influence of DNA conformation on radiation-induced single-strand breaks
β Scribed by Flavia Barone; Mauro Belli; Filomena Mazzei
- Publisher
- Springer-Verlag
- Year
- 1994
- Tongue
- English
- Weight
- 908 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0301-634X
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## Abstract The influence of singleβstrand breaks on the kinetics of the relaxation of DNA in a solution of low ionic strength has been investigated by a temperature jump method. The relaxation of DNA after a jump of 0.7 Β°C in the melting region has been monitored by measuring the extinction at 260
A widely accepted assumption in radiobiology is that ionizing radiation kills cells by inducing forms of damage in DNA structures that lead to the formation of lethal chromosome aberrations. One goal of radiation biology research is the identification of these forms of DNA damage, the characterizati