The influence of dissolved oxygen tensio
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M. Suphantharika; A. P. Ison; M. D. Lilly; B. C. Buckland
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Article
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1994
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John Wiley and Sons
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English
โ 491 KB
๐ 2 views
## Abstract The antibiotic, difficidin, and its hydroxylated derivative oxydifficidin, were synthesized by cultures of __Bacillus subtilis__ grown on a complex medium. Maximum titers of about 200 and 130 mg/L, respectively, were obtained. In fermentations where the dissolved oxygen tension (DOT) wa