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Influence of diet on the pattern of gastrointestinal biotransformation of netobimin and albendazole sulphoxide in sheep

✍ Scribed by G. Virkel; A. Lifschitz; A. Pis; C. Lanusse

Publisher
Springer-Verlag
Year
1999
Tongue
English
Weight
761 KB
Volume
24
Category
Article
ISSN
0378-7966

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πŸ“œ SIMILAR VOLUMES

Methimazole increases the plasma concent
Methimazole increases the plasma concentrations of the albendazole metabolites of netobimin in sheep
✍ Carlos E. Lanusse; Roger K. Prichard πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 502 KB

The influence of methimazole (MTZ) on the pharmacokinetics of netobimin (NTB) and its metabolites was investigated in adult sheep. NTB zwitterion suspension was administered at 20 mg kg-l by intraruminal injection either alone or with simultaneous administration of MTZ intramuscularly at 1.5 mg kg-l

Influence of surfactants on oral bioavai
Influence of surfactants on oral bioavailability of albendazole based on the formation of the sulphoxide metabolites in rats
✍ Pedro A. Redondo; Ana I. Alvarez; JosΓ© L. GarcΓ­a; Carlos Villaverde; Julio G. Pr πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 137 KB πŸ‘ 2 views

The influence of two surfactants, sodium taurocholate (STC) and polysorbate 80 (P80), on the bioavailability of albendazole (ABZ), orally administered to rats, has been studied. To assess the effect of the surfactants, they were administered at critical micellar and supramicellar concentrations, 5 a

Effect of amphiphilic surfactant agents
Effect of amphiphilic surfactant agents on the gastrointestinal absorption of albendazole in cattle
✍ Guillermo Virkel; Fernanda Imperiale; AdriΓ‘n Lifschitz; Alejandra Pis; Ana Alvar πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 124 KB πŸ‘ 2 views

## Abstract Albendazole (ABZ) is a widely used broad‐spectrum benzimidazole (BZD) anthelmintic. Low hydrosolubility and poor/erratic gastrointestinal (GI) absorption play against the systemic availability and resultant clinical efficacy of BZD compounds. Different strategies are currently investiga