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Influence of compound danshen tablet on the pharmacokinetics of losartan and its metabolite EXP3174 by liquid chromatography coupled with mass spectrometry

โœ Scribed by Yuan, Yongfang; Zhang, Hai; Ma, Weina; Sun, Sen; Wang, Benwei; Zhao, Liang; Zhang, Guoqing; Chai, Yifeng


Book ID
121703619
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
453 KB
Volume
27
Category
Article
ISSN
0269-3879

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Fingolimod (Gilenya ยฎ ; FTY720), has been recently approved for the treatment of multiple sclerosis in Europe and in the USA. In the present study, we have developed and validated a rapid and sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method to simultaneously quantify FTY720