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Influence of cofactor binding and active site occupancy on the conformation of the macromolecular substrate exosite of factor VIIa

โœ Scribed by Craig D Dickinson; Justin Shobe; Wolfram Ruf

Book ID
115628441
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
916 KB
Volume
277
Category
Article
ISSN
0022-2836

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## Abstract The role of some amino acids and metal ions in the catalytic activity of carbonic anhydrase (carbonate dehydratase EC 4.2.1.1) has been investigated. The additional stabilization of the transition state complex was used as the qualitative measure of the effect of molecular surrounding o