Inflammatory myofibroblastic tumor of the larynx

✍ Scribed by Sang-il Suh; Hae Young Seol; Jean Hwa Lee; Young Hen Lee; Taik-Kun Kim; Nam Joon Lee; Jeong-Soo Woo; In Sun Kim

• Publisher: John Wiley and Sons
• Year: 2006
• Tongue: English
• Weight: 196 KB
• Volume: 28
• Category: Article
• ISSN: 1043-3074
• DOI: 10.1002/hed.20413

✦ Synopsis

Background:

Inflammatory myofibroblastic tumor, composed of myofibroblastic spindle cells with acute and chronic inflammatory cells, is an unusual, benign solid mass that mimics a neoplastic process.

Methods:

We report a rare case of a patient with a laryngeal inflammatory myofibroblastic tumor. laryngoscopy demonstrated a submucosal mass involving the right false cord. the mass was a well-enhanced supraglottic lesion on ct scan. it showed medially high signal intensity and peripherally low signal intensity on t2-weighted mr images, and it displayed a high magnetization transfer ratio; before surgery, it was believed to be a malignant tumor. laryngoscopic biopsy was performed. pathologic features of the specimen were diagnostic for inflammatory myofibroblastic tumor.

Results:

Steroid therapy was chosen for further treatment. no recurrence was observed for 4 years.

Conclusion:

In patients with chronic hoarseness who have a malignant-looking submucosal laryngeal mass, inflammatory myofibroblastic tumor should be considered. conservative surgery and steroid treatment are advocated because of laryngeal preservation.