New pathogenic paradigms in inflammatory
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Antonio Di Sabatino; Paolo Biancheri; Laura Rovedatti; Thomas T. MacDonald; Gino
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Article
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2012
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John Wiley and Sons
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English
⚖ 78 KB
Recent progresses in basic science have opened new pathogenic scenarios in inflammatory bowel disease. The T helper cell type (Th)1/Th2 paradigm has been outdated thanks to the advances in understanding the function of Th17 cells. Innate immunity, nonimmune cells, and defective tolerogenic mechanism