Inflammation responsive degradation of crosslinked hyaluronic acid gels
β Scribed by Yui Nobuhiko; Okano Teruo; Sakurai Yasuhisa
- Book ID
- 113275461
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 703 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0168-3659
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Hyaluronic acid is a naturally occurring mucopolysaccharide. It is an important component of the intercellular matrix. It controls the permeability of tissues by means of the highly entangled network which can be formed because of its high molecular weight. To be able to use hyaluronic acid for seve
## Abstract Hydrogels, based on hyaluronic acid or hyaluronan (HA), are gaining attention as possible cellβscaffolding materials for the regeneration of a variety of tissues. This article describes how HA, a naturally occurring polymer, has been crosslinked to reduce its degradation rate and freeze
Hyaluronic acid (HA) was chemically crosslinked with glutaraldehyde (GA) to produce water-insoluble films having low water contents when brought into contact with water. The crosslinking reaction was performed using uncrosslinked HA films in acetone-water mixtures. This method could produce water-in