𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Inferring mode of inheritance by comparison of lod scores

✍ Scribed by Greenberg, David A.


Book ID
102701751
Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
753 KB
Volume
34
Category
Article
ISSN
0148-7299

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Effect of heterogeneity and assumed mode
✍ Durner, Martina ;Greenberg, David A. πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 597 KB

Heterogeneity is a major factor in many common, complex diseases and can confound linkage analysis. Using computer-simulated heterogeneous data we tested what effect unlinked families have on a linkage analysis when heterogeneity is not taken into account. We created 60 data sets of 40 nuclear famil

Linkage analysis assuming a single-locus
✍ David A. Greenberg; D. C. Rao πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 772 KB

## Abstract What happens to the results of linkage analysis when one assumes that a disease results from a single genetic locus with reduced penetrance when the actual cause is two epistatically interacting loci? We wanted to (1) determine whether assuming the correct mode of inheritance at the lin

Early onset periodontitis: A comparison
✍ Jeffrey C. Long; Walter E. Nance; Patsy Waring; John A. Burmeister; Richard R. R πŸ“‚ Article πŸ“… 1987 πŸ› John Wiley and Sons 🌐 English βš– 709 KB

Two rare types of familial periodontitis, a localized form usually diagnosed in late adolescence, and a more generalized form with a latter mean age of diagnosis, have been analyzed with respect to genetic models currently favored in the dental literature. These include autosomal recessive and X-lin

More powerful haplotype sharing by accou
✍ Andreas Ziegler; Adel Ewhida; Michael Brendel; AndrΓ© Kleensang πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 219 KB

## Abstract The concept of haplotype sharing (HS) has received considerable attention recently, and several haplotype association methods have been proposed. Here, we extend the work of Beckmann and colleagues [2005 Hum. Hered. 59:67–78] who derived an HS statistic (BHS) as special case of Mantel's