Studies have reported an association between homozygosity for a variant form of the methylenetetrahydrofolate reductase (MTHFR) gene and risk for neural tube defects. Because of MTHFR's involvement with folate metabolism and evidence that maternal use of a multivitamin with folic acid in early pregn
Infant C677T mutation inMTHFR, maternal periconceptional vitamin use, and risk of nonsyndromic cleft lip
β Scribed by Wyszynski, Diego F.; Diehl, Scott R.
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 7 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0148-7299
- DOI
- 10.1002/(sici)1096-8628(20000501)92:1<79::aid-ajmg14>3.0.co;2-h
No coin nor oath required. For personal study only.
β¦ Synopsis
Cleft lip with
π SIMILAR VOLUMES
The polymorphic mutation C677T in the gene of MTHFR is considered a risk mutation for spina bifida and vascular disease. Another common mutation on the MTHFR gene, A1298C, has also been described as another risk mutation. We studied the frequencies of these two mutations on DNA samples from healthy
Evidence for the teratogenicity of corticosteroids in humans is limited and has resulted in inconsistent recommendations regarding their use during early pregnancy. We examined the association between women's corticosteroid use during the periconceptional period (1 month before to 3 months after con
of sex ratios in children with different MTHFR