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Inefficient Peptide Binding by Cell-Surface Class II MHC Molecules

✍ Scribed by Melanie A. Sherman; Dominique A. Weber; Ellen A. Spotts; Joseph C. Moore; Peter E. Jensen


Book ID
112239864
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
263 KB
Volume
182
Category
Article
ISSN
0008-8749

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he allele-specific peptidebinding motifs of major histocompatibility complex (MHC) proteins, originally discovered by pool sequencing of MHC class I-bound peptides 1 , provide a biochemical basis for the phenomenon of MHC restriction of T-cell responses. However, the analysis of class II peptide mot