𝔖 Bobbio Scriptorium
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Industrial production of monoclonal antibodies and therapeutic proteins by dialysis fermentation

✍ Scribed by Michael J. Comer; Michael J. Kearns; Jürgen Wahl; Michael Munster; Thomas Lorenz; Berthold Szperalski; Stefan Koch; Ulrich Behrendt; Herwig Brunner

Publisher
Springer
Year
1990
Tongue
English
Weight
288 KB
Volume
3
Category
Article
ISSN
0920-9069

No coin nor oath required. For personal study only.

✦ Synopsis

A novel and powerful fermentation method is reported for the large-scale growth of mammalian cells and their secreted products. The system described illustrates many of the advantages of conventional batch fermentation processes but in addition has been shown to yield cell densities in excess of 1 x 10(7) cells/ml with concomitant increase in product concentration.

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