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Induction of unscheduled DNA synthesis by chemical mutagens in spermatogenic cells of the mouse in vitro

โœ Scribed by H. Beikirch


Book ID
113248956
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
148 KB
Volume
46
Category
Article
ISSN
0165-1161

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Induction of unscheduled DNA synthesis b
โœ H. Beikirch ๐Ÿ“‚ Article ๐Ÿ“… 1977 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 357 KB

Testicular cells of male mice were isolated, and the incorporation of tritium labeled thymidine into the DNA of the cells was estimated after exposure to various chemical mutagens. The normal semiconservative DNA synthesis was suppressed by the addition of hydroxyurea. Thirteen compounds were tested