Induction of the SOS response by hydroxyurea in Escherichia coli K12
✍ Scribed by Jordi Barbé; Antonio Villaverde; Ricardo Guerrero
- Book ID
- 113254998
- Publisher
- Elsevier Science
- Year
- 1987
- Weight
- 238 KB
- Volume
- 192
- Category
- Article
- ISSN
- 0165-7992
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When Escherichia coli is subjected to treatments that damage DNA or perturb DNA replication considerable cell filamentation occurs. It has been postulated that this phenomenon is associated with the presence of a division inhibitor induced coordinately with the SOS functions. The role of this induct
## Abstract The SOS system in __Escherichia coli__ is induced in response to DNA damage and the arrest of DNA synthesis. Here we show that in AB1157 bacteria starved for arginine, conditions for induction of adaptive mutations, the LexA‐dependent SOS system is induced, but that this occurs only whe