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Induction of the growth inhibitor IGF-binding protein 3 by p53

✍ Scribed by Buckbinder, Leonard; Talbott, Randy; Velasco-Miguel, Susana; Takenaka, Ivone; Faha, Barbara; Seizinger, Bernd R.; Kley, Nikolai


Book ID
109794247
Publisher
Nature Publishing Group
Year
1995
Tongue
English
Weight
965 KB
Volume
377
Category
Article
ISSN
0028-0836

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Insulin-like growth factor binding protein (IGFBP)-3 effects proliferation and differentiation of numerous cell types by binding to insulin-like growth factors (IGF) and attenuating their activity or by directly affecting cells in an IGFindependent manner. Consequently, IGFBPs produced by specific c