Induction of T cell activity in athymic (nu/nu) mice infected with Trypanosoma rhodesiense
β Scribed by Jean Langhorne; Florence M. Rollwagen; John F. Finerty
- Book ID
- 113132648
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- English
- Weight
- 536 KB
- Volume
- 81
- Category
- Article
- ISSN
- 0008-8749
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Mice carrying the nude mutation (nu/nu) lack a functioning thymus and do not contain detectable levels of immunocompetent T cells. We now report that nu/nu mice do have lymphocytes which can be activated __in vivo__ by heterologous erythrocytes and a Lytβ1 T cellβderived factor (interle
Although the athymic nude mouse is grossly deficient in peripheral T cells, the number of lymphocytes bearing T-cell markers (L3T4, LyT2) and the alpha beta or gamma delta T-cell receptor (Tcr) increases steadily with age. The anatomical site(s) where these cells arise are unknown. Splenocytes from