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Induction of sister-chromatid exchanges by DNA-damaging agents and 12-O-tetradecanoyl-phorbol-13-acetate (TPA) in synchronous Chinese hamster ovary (CHO) cells

✍ Scribed by Hatsumi Nagasawa; Donald Fornace; John B. Little


Book ID
113192589
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
631 KB
Volume
107
Category
Article
ISSN
0027-5107

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The effect of the tumour promoter 12-O-t
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## Abstract The induction of sister chromatid exchanges (SCE) by the tumour promoter 12‐O‐tetradecanoyl‐phorbol‐13‐acetate (TPA) has been studied in V79 Chinese hamster cells comparing control untreated cells with either UV‐irradiated or MNNG‐treated cells. In untreated cells TPA induced SCE at a v