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Induction of SCE by DNA cross-links in human fibroblasts exposed to 8-MOP and UVA irradiation

✍ Scribed by Anders Bredberg; Bo Lambert


Book ID
119092571
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
764 KB
Volume
118
Category
Article
ISSN
0165-1218

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Levels of DNA strand breaks and DNA-protein cross-links (DPCs) were measured using the alkaline elution assay in normal human skin fibroblasts irradiated with 0-200 J m-2 of 254 nm UV radiation and incubated for 0-24 h. On incubation, the yields of both single-strand breaks (SSBs) and DPCs increased