Induction of splice correction by cell-p
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Samir El-Andaloussi; Henrik J. Johansson; Pontus Lundberg; Ülo Langel
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Article
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2006
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John Wiley and Sons
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English
⚖ 281 KB
👁 1 views
## Abstract ## Background Directing splicing using oligonucleotides constitutes a promising therapeutic tool for a variety of diseases such as β‐thalassemia, cystic fibrosis, and certain cancers. The rationale is to block aberrant splice sites, thus directing the splicing of the pre‐mRNA towards t