Induction of remission in acute leukemia with prednisone and intravenous methotrexate
β Scribed by Charles A. Brubaker; Gerald S. Gilchrist; Denman Hammond; Carol B. Hyman; Nomie A. Shore; Kenneth O. Williams
- Book ID
- 118535548
- Publisher
- Elsevier Science
- Year
- 1968
- Tongue
- English
- Weight
- 229 KB
- Volume
- 73
- Category
- Article
- ISSN
- 1097-6833
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## Background: The authors report the occurrence of fatal or near-fatal sepsis in 16 of 38 children with newly diagnosed acute lymphoblastic leukemia (all) treated with a new induction regimen that differed from its predecessor by the substitution of dexamethasone for prednisone. ## Methods: The
## Abstract Fortyβfive children with acute nonlymphoblastic leukemia in relapse received a total of 56 courses of Lβasparaginase combined with vincristine and prednisone. The complete remission rate of 40% (12 of 30 trials) in patients resistant to vincristine and prednisone was almost identical to