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Induction of physical dependence in rats by ethanol inhalation without the use of pyrazole

✍ Scribed by A.P. Ferko; E. Bobyock

Book ID
119002437
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
544 KB
Volume
40
Category
Article
ISSN
0041-008X

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Induction of physical dependence in rats
Induction of physical dependence in rats by short interval medication
✍ Yoshihiko Koga πŸ“‚ Article πŸ“… 1976 πŸ› Springer 🌐 English βš– 370 KB

Rats were intermittently medicated at one hour intervals through an implanted intravenous cannula. Physical dependence on morphine and codeine was developed rapidly and it was detectable with the maintenance dose as low as 9.6 mg/kg/day. Physical dependence on pentazocine was also developed with the