๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Induction of P450 3A1/2 and 2C6 by gemfibrozil in Sprague-Dawley rats

โœ Scribed by Liu, Aiming; Yang, Julin; Zhao, Xin; Jiao, Xiaolan; Zhao, Weihong; Ma, Qing; Tang, Zhiyuan; Dai, Renke

Book ID
122315933
Publisher
Elsevier
Year
2011
Tongue
English
Weight
241 KB
Volume
63
Category
Article
ISSN
1734-1140

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Effects of age and pregnancy on cytochro
Effects of age and pregnancy on cytochrome P450 induction by octamethyltetracyclosiloxane in female Sprague-Dawley rats
โœ Charles N. Falany; Ge Li ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 249 KB

## Abstract Dimethylcyclosiloxanes (DMCS) are components of silicone gel containing implants and are known inducers of human drug metabolizing enzymes. The effects of the major DMCS, octamethyltetracyclosiloxane (D4) on cytochrome P450 (CYP) induction were examined in young adult, mature, and pregn

Metabolism and Distribution of [2,3-14C]
Metabolism and Distribution of [2,3-14C]Acrolein in Sprague-Dawley Rats
โœ Richard A. Parent; Halina E. Caravello; Dale E. Sharp ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 820 KB

The metabolism and disposition of [2,3-'4C]acrolein was studied in Sprague-Dawley rats after oral or intravenous dosing. Four groups of ten rats (five male and five female) were dosed with radiolabeled acrolein intravenously at 2.5 mg kg-' (Group 2), orally by gavage at 2.5 mg kg-I, either as a sing