Effects of age and pregnancy on cytochro
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Charles N. Falany; Ge Li
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Article
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2005
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John Wiley and Sons
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English
⚖ 249 KB
## Abstract Dimethylcyclosiloxanes (DMCS) are components of silicone gel containing implants and are known inducers of human drug metabolizing enzymes. The effects of the major DMCS, octamethyltetracyclosiloxane (D4) on cytochrome P450 (CYP) induction were examined in young adult, mature, and pregn